- Prior history of gastrointestinal bleeding or gastrointestinal ulceration within the past year
- Mechanical ventilation > 48 hours or acute respiratory failure requiring BIPAP/high flow nasal cannula
- Significant coagulopathy that is not medication induced
- (INR > 1.5, platelets < 50,000/m3, aPTT > 2x control)
- Hypoperfusion defined as:
- Requiring vasopressor/inotrope support
- Lactic acid ≥ 2 mmol/L
- Admitted due to multiple trauma (ISS ≥ 16), traumatic brain, or spinal cord injury
- Intracranial hemorrhage or ischemic stroke on this admission
- Admitted due to acute major burn injury (> 20% of body surface area)
- Atrial fibrillation ablation procedure in the last 30 days
GI prophylaxis is recommended.
Evaluate next day.
If any of the following minor criteria apply, choose them, then follow the recommendation in the result section below:
-
NPO order
-
High daily dose corticosteroids (> 250mg hydrocortisone, >62.5mg prednisone, 50mg
methylprednisolone, 9.375mg dexamethasone)
-
Two or more antiplatelet agents
- Antiplatelet agents include: aspirin, cilostazol, clopidogrel, prasugrel,
ticagrelor,
vorapaxar, anagrelide, cangrelor, and ticlodipine
-
ICU length of stay > 1 week
-
Systemic anticoagulation (excluding DVT [deep vein thrombosis]
prophylaxis)
-
Post-op inpatient surgery
-
Hepatic failure/cirrhosis
-
Acute renal failure
Result:
NONE selected. GI prophylaxis is NOT indicated. Evaulate next day.
Additionally, patients should be continued on acid suppressive therapy if any of the following history exists in updated note documentation:
- GERD (gastroesophageal reflux disease)
- PUD (peptic ulcer disease)
- Helicobacter pylori infection
- Esophagitis
- Dyspepsia
- Hypersecretory or acid diseases (e.g. Zollinger-Ellison Syndrome)